IGF-1 LR3 (Insulin-like Growth Factor 1 Long Arg3) is a synthetic form of IGF-1, a protein that plays a key role in growth, development, and cellular repair. It’s similar to the naturally occurring IGF-1 in your body but has a longer half-life due to a modification in its structure—specifically, the substitution of the amino acid arginine at position 3.

Because of this modification, IGF-1 LR3 stays in the bloodstream for a longer period of time, allowing for more extended biological effects. It’s often used in the bodybuilding and fitness community for its potential to promote muscle growth, increase fat loss, and improve recovery.

Benefits (Research Focus)

• IGF-1 receptor activation — studied for selective high-affinity agonism of the IGF-1 receptor
• PI3K/Akt/mTOR signaling — investigated for downstream activation of cellular growth and protein synthesis pathways
• Reduced IGFBP binding — explored for the Arg³ substitution that decreases IGF-binding protein affinity
• Extended half-life — examined for ~20-30 hour bioactivity window compared to ~15 minutes for native IGF-1
• Skeletal muscle research — researched for satellite cell activation and protein synthesis endpoints in preclinical models

Disclaimer

• This product is intended for laboratory research use only.
• Not for human or veterinary use.
• Not approved for diagnostic, therapeutic, or medical applications.
• Handle using appropriate laboratory safety procedures and personal protective equipment.