(MT-II) is a synthetic, cyclic heptapeptide analogue of the naturally occurring α-melanocyte-stimulating hormone (α-MSH). Originally engineered at the University of Arizona it is heavily studied for its super potent, non-selective activation of the central and peripheral melanocortin receptor systems. Unlike endogenous hormones, its structural modifications grant it robust resistance to enzymatic degradation, allowing researchers to explore its multi-systemic pathways involving skin pigmentation, sexual health, and metabolic regulation.

Benefits (Research Focus)

• Non-selective receptor agonism — evaluated for its binding affinity across MC1R, MC3R, MC4R, and MC5R receptor pathways.
• Melanogenesis facilitation — studied for direct MC1R activation on melanocytes to trigger eumelanin synthesis independent of heavy UV exposure.
• Erectogenic mechanisms — investigated for central nervous system signaling (primarily via MC3R/MC4R) that stimulates erectile function and libido.
• Appetite homeostasis — explored for MC4R-mediated metabolic signaling pathways that suppress food intake and influence energy expenditure.
• Cyclic peptide stability — engineered with a rigid lactam bridge structure to resist fast proteolysis and sustain active plasma half-life.

⚠️ Disclaimer

• This product is intended for laboratory research use only.
• Not for human or veterinary use.
• Not approved for diagnostic, therapeutic, or medical applications.
• Handle using appropriate laboratory safety procedures and personal protective equipment.